Medicine-Drugs

Salbutamol Dosage, Uses, Side effects, contraindications

Uses, Dosage, Side effects, contraindications, Precautions, Interactions and warnings of Salbutamol.

Description of Salbutamol

Salbutamol is a bronchodilator drug that relaxes the muscles of the airways leading to the lung and improves the amount of air flow to and from the lungs. It is used to prevent the symptoms of asthma and Chronic obstructive pulmonary diseases.

Salbutamol is also given to treat cough, wheeze and difficulty breathing caused by certain respiratory problems.

This medicine also comes in an inhaler which is usually blue in color.

Salbutamol is sometimes given as a form of  tablets, capsules or syrup for patients who can’t use an inhaler very well.

It may also be given using a Nebuliser, but this is usually only if you have severe asthma or COPD.


Salbutamol Classification and General Details.

  • Category : Adrenergic Bronchodilators
  • Schedule : Schedule “H”
  • Also Known asAlbuterol
  • Prescription : Required
  • Legal Status : Approved
  • Available as : Tablets, Solution, Injection, Respules, Drops
  • Brand Names : ProAir RespiClick, Salbebtol, Asthalin SA

Uses of Salbutamol

Why Salbutamol is prescribed for?

Acute asthma

This drug is prscribed to prevent or treat acute attacks of asthma characterized by a sudden and severe difficulty in breathing.

Asthma

It is used to prevent or reverse airway obstruction in patients who suffer from asthma or reverse airway obstruction due to bronchospasm.

Bronchitis

Salbutamol is given to relieve and prevent the symptoms of this condition where the walls of the airways swell, making breathing very difficult.

Chronic obstructive pulmonary disease – COPD

Albuterol is given to prevent and treat the symptoms associated with a group of lung diseases that block airflow and make it very difficult to breathe.

Uncomplicated preterm labor

Albuterol is also sometimes given to prevent and delay labor in cases where the chances of premature birth are very high.


How to use Salbutamol?

Read the Patient Information Leaflet given by your doctor before you start using this medication.

Inhale this drug by mouth as directed by your doctor, usually every 4 to 6 hours as needed.

Do not increase dose or use this drug more often than prescribed without your doctor’s consultation.

If you are using this drug to prevent asthma caused by exercise, use it 20 to 30 minutes before exercise.

Always keep this quick-relief inhaler with you for emergency situation.


Side effects / Adverse Effects

what are the Major & minor side effects for Salbutamol ?

Most common side effects:

Some of the common side effects that can occur with salbutamol include:

  • fast or irregular heart rate
  • nausea
  • vomiting
  • shakiness
  • chest pain
  • nervousness
  • sore throat
  • runny nose
  • headache
  • dizziness
  • Agitation and anxiety
  • Difficulty in passing urine

Severe side effects

Tightening and swelling of the muscles around your airways, Symptoms include:

  • trouble breathing
  • wheezing

Serious allergic reactions

  • hives
  • skin rash
  • swelling of face, eyelids, lips, tongue, or throat
  • trouble in swallowing
  • worsening of your breathing problems like wheezing, chest tightness, or shortness of breath
  • shock (loss of blood pressure / consciousness)

Heart problems

  • faster heart rate
  • higher blood pressure (BP)

Severe skin reactions includes

  • Itching
  • fever
  • chills
  • burning
  • red lesions

When not to use?

Contraindications of Salbutamol

Albuterol is not recommended for use if you have a known history of allergy to Salbutamol drug or any other component present along with it.


What special precautions should I follow?

Before taking Salbutamol ..

Tell your doctor if you are allergic to it or similar medicines like  levalbuterol, metaproterenol, salmeterol or if you have any other known allergies.

Before using this drug, report your doctor about your medical history, for example:

  • Angina
  • Heart Attack
  • High BP
  • Seizure

This medicine may make you dizzy, combined with Alcohol can make you more dizzy so Do not drive, or operate machinery during this therapy.

During pregnancy, this drug should be given only when clearly needed.

Consult your doctor if you are breast-feeding.


Dosage and Administration of Salbutamol

The Dosage of this drug will depend on:

Dosage for Bronchospasm :

Adult dosage (for, ages 18–64 years)

The ideal dosage is 2 inhalations taken by mouth every 4–6 hours. Some people may only need 1 inhalation for every 4 hours.

Child dosage (for, ages 4–17 years)

The idal dosage is 2 inhalations taken by mouth every 4–6 hours. few people may only need 1 inhalation every 4 hours.

Child dosage (for, ages 0–3 years)

The safety and effectiveness of this medicine hasn’t been established in children younger than 4 years of age.

Senior dosage (for, ages 65 years and older)

Older adults may process medicine more slowly. A normal adult dose may cause levels of the drug to be higher than the normal. If you’re a senior, you may need a quite lower dose or a different schedule.

Dosage to prevent exercise-related asthma

Adult dosage (for, ages 18–64 years)

The ideal dosage is 2 inhalations taken by mouth, taken 15–30 minutes before starting exercise.

Child dosage (for, ages 4–17 years)

The ideal dosage is 2 inhalations taken by mouth, taken 15–30 minutes before starting exercise.

Child dosage (for, ages 0–3 years)

The safety and effectiveness of this medicine hasn’t been established in children younger than 4 years of age.

Senior dosage (for, ages 65 years and older)

Older adults may process medicine more slowly. A normal adult dose may cause levels of the drug to be higher than the normal. If you’re a senior, you may need a quite lower dose or a different schedule.


Interaction of Salbutamol

Drug/Food and Alcohol interactions may change “how your medications work” or “increase the risk for severe side / Adverse effects”. 

This medicine may interact differently for person to person and condition to condition.

You should ask for all the possible interactions with your doctor before starting this medicine.

Interaction with Alcohol : 

Interaction with alcohol is unknown but consuming alcohol during Salbutamol therapy may make you Dizzy. It is Recommended to consult your doctor before consumption.

Interaction with Medicine :

Amitriptyline : MODERATE

Atenolol : MODERATE

Xylometazoline : MODERATE

Furosemide : MODERATE

Hydrochlorothiazide : MODERATE

Ketoconazole : MODERATE

Formoterol : MODERATE

Azithromycin : MODERATE

Insulin and other anti diabetic medicines : MODERATE

Mifepristone : SEVERE

Propranolol : SEVERE

Disease interactions :

Diabetes

Use of this drug has been associated with a mild to moderate rise in blood sugar levels in most patients. Hence, caution should be taken if the patient is diabetic.

Heart disease

Use of this drug has been associated with an increase in heart rate and changes in BP. It should be used with caution in patients with an active or past case of heart disease. Patients should also be screened for the risk factors of heart disease before giving the treatment course.

Kidney Disease

Salbutamol should be used with caution in patients having an impairment of normal kidney function. The dose must be selected carefully and the kidney functions should be monitored on a regular basis.

Hypokalemia

Use of Albuterol has been associated with a decrease in blood potassium levels. It should be used with caution in patients having a potassium levels in the body are imbalanced.

Seizures

This drug must be administered with caution in patients with seizure disorders as the risk of increased frequency and severity of convulsions are significantly high.

Food interactions :

Salbutamol should be used with caution if you are using mineral oil / castor oil as a laxative. The risk of adverse effects are significantly high and so usage should be reported before starting the treatment therapy with Salbutamol.


Salbutamol During Pregnancy

Salbutamol is generally considered as a safe drug to use in pregnancy but still this medicine is not recommended for use in pregnant women unless absolutely necessary. Consult the doctor and discuss the risks and benefits of using this medication before using this medicine.

Some women may feel that their asthma gets better during pregnancy, while some see no change at all, and for few others it will be worse.

If woman have asthma, doctor will most likely recommend to continue to use Salbutamol inhaler during pregnancy as The risks of facing serious asthma attacks during pregnancy are much worse than the risks of using salbutamol.


Salbutamol During Breast-Feeding 

Salbutamol may pass into breast milk in quite small amounts so it is not recommended for use in breastfeeding women as the effect on the nursing infant is not clinically established.

Your doctor may ask you to discontinue breastfeeding if the use of this medication is necessary.


General warnings

Other diseases

Report your doctor regarding your medical history before starting this medication for safe intake.

Hypokalemia

Use of this drug can cause a decrease in blood potassium levels and hence should be administered with caution in patients facing  Hypokalemia.

Paradoxical bronchospasm

Use of this medication has been associated with worsening of asthma symptoms in some instances. Report your doctor immediately if breathing becomes more difficult after using this drug. The use of medicine should stop immediately in such cases.

Excessive use

It is recommended to use this medicine in prescribed quantities only as excessive use may cause some severe adverse/side effects and may prove fatal in some cases.

Milk protein allergy

This medicine should not be given to patients who have a history of allergy to milk proteins.

Use in elderly

This medicine should be used with high caution in the elderly as the risk of adverse effects are significantly high.

Use in children

Safety and efficacy are established based on the form of the medicine and age of the child. All the recommendations should be strictly followed while prescribing this medicine in children.

Other medicines

Report the use of all medications including herbs and supplements to the doctor before getting Salbutamol.


How Salbutamol works?

Salbutamol / Albuterol is a bronchodilator. Salbutamol works by relaxing the muscles in the airways and widens airways hence it opening air passages in the lungs to makes breathing easier.


Expert Advice for Salbutamol

Use Albuterol inhalation exactly same as prescribed by your doctor. Do not use in higher or smaller amounts or for longer than recommended.

Always keep inhaler upright during the loading of the dose / administration steps.

If you feel a slightly sweet tasting powder in your mouth after inhaling the medicine, you have received the dose and the active substance has reached your lungs.

During use, regularly wipe the mouth piece with a soft clean cloth.

Always replace inhaler cap after you have used the inhaler.

Always report your doctor if you suffer from an over active thyroid gland.

Take special precaution in case of you experience chest pains.

Take special care with salbutamol if you already suffering from any disease of the heart.


Other Important Details 

Onset of action (duration of time it takes for a drug’s to come in effects)

The peak effect of this drug can be observed within 5 minutes when taken via inhalation, and for oral administration the duration is 30 minutes.

Duration of effect

The effect of this drug lasts for an average duration of 3 – 4 Hours while Inhalation forms remain effective for a lesser duration in comparison with the oral forms.

Is it habit forming?

Yes, high Habit forming tendency has been reported.

Storage

Store metered dose inhaler at room temperature with the mouthpiece down and keep drug between 15 -25 Degree Celsius temperature. please Keep it away from extreme heat or cold


Common Questions / FAQs

Is Salbutamol drug a steroid/ an antibiotic/ a cough syrup/ a betablocker/ contains steroid/ addictive/ a rescue inhaler?

Salbutamol is a beta receptor agonist used to prevent and treat wheezing, difficulty breathing, chest tightness, and coughing caused by lung diseases such as asthma and chronic obstructive pulmonary disease. It is a rescue inhaler for asthma problem. and it’s not a steroid or an antibiotic. It is also not an addictive drug

Is Salbutamol / Albuterol safe/ safe for child?

Salbutamol / Albuterol is safe if it is used at prescribed doses for the prescribed duration as advised by doctors.

Does Salbutamol / Albuterol need a prescription?

Yes

Does Salbutamol or Albuterol relieve symptoms of coughing, wheezing, and breathlessness?

Yes, Salbutamol / Albuterol is used in relieving acute symptoms of coughing, wheezing, and breathlessness.

Does Salbutamol / Albuterol cause drowsiness/ increased heart rate/ increase blood pressure/ or weight gain?

Salbutamol / Albuterol may cause light headedness, and increased heart rate or increased BP – blood pressure; however it is not known to cause drowsiness or weight gain. Report your doctor if you experience any of such side effects.

Thank you for reading detailed article on Salbutamol, you can also read Diazepam, Alprazolam, Ibuprofen

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